SLC1A5 prevents aortic aneurysm and dissection by glutaminolytic-epigenetic orchestration of vascular smooth muscle cell homeostasis [RNA-seq]
RNA-seq (gene expression) · mouse · 16 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 16 samples: 8 × Saline vs 8 × Ang IIGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- SLC1A5 prevents aortic aneurysm and dissection by glutaminolytic-epigenetic orchestration of vascular smooth muscle cell homeostasisNature communications · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE309259_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1334836 and SRA study SRP627870. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 2 replicated groups read from 16 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9264053 Saline 1 Saline
- GSM9264054 Saline 2 Saline
- GSM9264055 Saline 3 Saline
- GSM9264056 Saline 4 Saline
- GSM9264057 Saline 5 Saline
- GSM9264058 Saline 6 Saline
- GSM9264059 Saline 7 Saline
- GSM9264060 Saline 8 Saline
- GSM9264061 Ang II 1 Ang II
- GSM9264062 Ang II 2 Ang II
- GSM9264063 Ang II 3 Ang II
- GSM9264064 Ang II 4 Ang II
- GSM9264065 Ang II 5 Ang II
- GSM9264066 Ang II 6 Ang II
- GSM9264067 Ang II 7 Ang II
- GSM9264068 Ang II 8 Ang II
- GSE318897 L-DOPA treatment promotes sustained neurovascular and synaptic homeostasis in the diabetic retina 53 samples shares homeostasis, vascular
- GSE299766 Effect of SLC1A5 overexpression on T cell metabolism and function 12 samples shares slc1a5
- GSE228579 Chronic stress disrupts hepatic homeostasis and accelerates liver cancer progression through ADRB2 signaling 66 samples shares homeostasis
- GSE279885 Perimenopausal State Oestradiol to Progesterone Imbalance Drives Alzheimer’s Risk via ERRα Dysregulation and Energy Dyshomeostasis 59 samples shares homeostasis
- GSE338894 An orally active, gut-enriched AhR agonist demonstrates therapeutic efficacy in colitis through regulation of inflammation, barrier homeostasis, and fibrosis 50 samples shares homeostasis
- GSE283571 Circadian reprogramming of protein homeostasis and glycolipid metabolism in diabetic nephropathy 47 samples shares homeostasis
- GSE276270 NOTCH-driven oscillations control cell fate decisions during intestinal homeostasis 36 samples shares homeostasis
- GSE100048 m6A mRNA methylation controls T cell homeostasis by targeting IL-7/STAT5/SOCS pathway 36 samples shares homeostasis
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.