GEO series
Bulk RNA sequencing analysis of VZV-infected microglia
GSE309260
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2026/05/27
GPL24676
Summary
Varicella-zoster virus (VZV) infection alters microglial function and contributes to neuroinflammation. To investigate these effects, cell-free VZV was prepared and used to infect two transformed human microglial cell lines (HMC3) and human embryonic stem cell-derived microglia (ESC-MG). Bulk RNA sequencing was performed on HMC3 at 48 hours post-infection to characterize the host transcriptional response.
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Paper (PMID 42177488) ↗
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