ΔNp73 isoform defines a TP53mutant-like poor risk subgroup of acute myeloid leukemia
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 11 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Topic
- Acute myeloid leukemiaThis series is part of our curated briefing on it.
- Samples
- 11 samples: 2 × MOLM13 empty vecto vs 2 × MOLM13 DNp73-OE vs 2 × MOLM13 KOGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- ΔNp73 isoform defines a TP53-mutant-like poor-risk subgroup of acute myeloid leukemiaCell reports. Medicine · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE310074_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1365095 and SRA study SRP645240. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 6 samples.
How we read this: 3 replicated groups read from 11 sample titles; they account for 6 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9287775 MOLM13 empty vector 1 MOLM13 empty vecto
- GSM9287776 MOLM13 empty vector 2 MOLM13 empty vecto
- GSM9287777 MOLM13 DNp73-OE 1 MOLM13 DNp73-OE
- GSM9287778 MOLM13 DNp73-OE 2 MOLM13 DNp73-OE
- GSM9287779 MOLM13 KO 1 MOLM13 KO
- GSM9287780 MOLM13 KO 2 MOLM13 KO
- GSM9287781 MOLM13_EV ChIP TP53ab
- GSM9287782 MOLM13_DNp73_OE ChIP TP53ab
- GSM9287783 MOLM13_DNp73_OE ChIP DNp73ab
- GSM9287784 MOLM13_EV ChIP TAp73ab
- GSM9287785 MOLM13_DNp73_OE ChIP TAp73ab
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.