Platelet lncRNA LUCAT1 Associates with Risk of Major Adverse Cardiovascular Events
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 4 × CD34+ MKs, PBS, D vs 4 × CD34+ MKs, IFNα 1000 U/mL, D vs 4 × CD34+ MKs, IFNγ 100 ng/mL, DGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE310096_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1365134 and SRA study SRP645288. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 3 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9288096 CD34+ MKs, PBS, D1 CD34+ MKs, PBS, D
- GSM9288097 CD34+ MKs, PBS, D2 CD34+ MKs, PBS, D
- GSM9288098 CD34+ MKs, PBS, D3 CD34+ MKs, PBS, D
- GSM9288099 CD34+ MKs, PBS, D4 CD34+ MKs, PBS, D
- GSM9288100 CD34+ MKs, IFNα 1000 U/mL, D1 CD34+ MKs, IFNα 1000 U/…
- GSM9288101 CD34+ MKs, IFNα 1000 U/mL, D2 CD34+ MKs, IFNα 1000 U/…
- GSM9288102 CD34+ MKs, IFNα 1000 U/mL, D3 CD34+ MKs, IFNα 1000 U/…
- GSM9288103 CD34+ MKs, IFNα 1000 U/mL, D4 CD34+ MKs, IFNα 1000 U/…
- GSM9288104 CD34+ MKs, IFNγ 100 ng/mL, D1 CD34+ MKs, IFNγ 100 ng/…
- GSM9288105 CD34+ MKs, IFNγ 100 ng/mL, D2 CD34+ MKs, IFNγ 100 ng/…
- GSM9288106 CD34+ MKs, IFNγ 100 ng/mL, D3 CD34+ MKs, IFNγ 100 ng/…
- GSM9288107 CD34+ MKs, IFNγ 100 ng/mL, D4 CD34+ MKs, IFNγ 100 ng/…
- GSE302674 Platelet Activation and a Platelet Biosignature Associates with Enhanced Cardiovascular Risk in Patients with Controlled Psoriasis. 91 samples shares cardiovascular, associates, platelet
- GSE288489 LncRNA LUCAT1 and exosomal MIF induced by Helicobacter pylori promotes M2 macrophage polarization in gastric cancer 12 samples shares lucat1, lncrna
- GSE255501 LncRNA LUCAT1 Promotes Glioblastoma Progression by Enhancing HIF1⍺ Activity [RNA-seq] 8 samples shares lucat1, lncrna
- GSE255502 LncRNA LUCAT1 Promotes Glioblastoma Progression by Enhancing HIF1⍺ Activity [ChIP-seq] 8 samples shares lucat1, lncrna
- GSE232027 Platelet Reactivity ExpreSsion Score Predicts Cardiovascular Risk 84 samples shares cardiovascular, platelet
- GSE308951 A platelet transcriptomic signature of thromboinflammation predicts cardiovascular risk 38 samples shares cardiovascular, platelet
- GSE320559 LUCAT1 Drives Arecoline-Induced Head and Neck Cancer Progression via STAT1-Mediated Transcriptional Regulation 4 samples shares lucat1
- GSE68086 RNA-seq of tumor-educated platelets enables blood-based pan-cancer, multiclass and molecular pathway cancer diagnostics 285 samples shares platelet
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.