Kaempferol Attenuates Spaceflight-associated Knee Cartilage Degeneration by Targeting NOX4-Mediated Mitochondrial Dysfunction
RNA-seq (gene expression) · human · 9 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 9 samples: 7 distinct titles, 1 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Kaempferol Attenuates Spaceflight-Associated Knee Cartilage Degradation by Targeting NOX4-Mediated Mitochondrial DysfunctionAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE310264_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1365659 and SRA study SRP646175. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 9 sample titles: 7 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9293058 Rotary_Culture_Gel_1_resub
- GSM9293059 Rotary_Culture_Gel_2_resub
- GSM9293060 Rotary_Culture_Gel_3_resub
- GSM9293061 Rotary_Culture_Gel_Plus_Kaempferol1
- GSM9293062 Rotary_Culture_Gel_Plus_Kaempferol2
- GSM9293063 Rotary_Culture_Gel_Plus_Kaempferol3
- GSM9293064 Static_Culture_Gel_1_resub
- GSM9293065 Static_Culture_Gel_2_resub
- GSM9293066 Static_Culture_Gel_3_resub
- GSE279133 MYC plus class IIa HDAC inhibiton potentiates mitochondrial dysfunction in non-small cell lung cancer [RNA-seq] 64 samples shares mitochondrial, dysfunction
- GSE343456 MCART1 (SLC25A51) deficiency exacerbates mitochondrial dysfunction during MPP+-induced complex I stress 24 samples shares mitochondrial, dysfunction
- GSE304575 LMNA p.H222P mutation causes contractile dysfunction via impaired mitochondrial calcium uptake in human cardiac laminopathy 12 samples shares mitochondrial, dysfunction
- GSE307925 Proliferative diabetic retinopathy subtypes defined by immune defense and endothelial mitochondrial dysfunction 12 samples shares mitochondrial, dysfunction
- GSE338415 Loss of TSPOAP1 exacerbates mitochondrial dysfunction and neuronal apoptosis after intracerebral hemorrhage 10 samples shares mitochondrial, dysfunction
- GSE327103 Glabridin Promotes Melanosome Degradation and Alleviates Melanosome-Induced Mitochondrial Dysfunction in Keratinocytes via Autophagy 9 samples shares mitochondrial, dysfunction
- GSE226975 Mitochondrial Dysfunction and Increased Reactive Oxygen Species Production in MECP2 Mutant Astrocytes and their Impact on Neurons 12 samples shares mitochondrial, dysfunction
- GSE259286 In vitro modeling of nutritional and mitochondrial-targeted therapies for osteosarcoma 98 samples shares mitochondrial
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.