Wnt-materials sustain H3K14-acetylation in human skeletal stem cells for tissue engineering and bone repair
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 26 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 26 samples: 4 × ATACseqA vs 4 × ATACseqI vs 3 × A vs 3 × IGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE310737_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1367000 and SRA study SRP647246. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 14 samples.
How we read this: 4 replicated groups read from 26 sample titles; they account for 14 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9307733 ATACseqA1 ATACseqA
- GSM9307734 ATACseqA3 ATACseqA
- GSM9307735 ATACseqA4 ATACseqA
- GSM9307736 ATACseqA5 ATACseqA
- GSM9307737 ATACseqI1 ATACseqI
- GSM9307738 ATACseqI2 ATACseqI
- GSM9307739 ATACseqI3 ATACseqI
- GSM9307740 ATACseqI4 ATACseqI
- GSM9307741 K14_A1_L1
- GSM9307742 K14_A2_L1
- GSM9307743 K14_A3_L1
- GSM9307744 K14_I1_L1
- GSM9307745 K14_I2_L1
- GSM9307746 K14_I3_L1
- GSM9307747 K27_A1_L1
- GSM9307748 K27_A2_L1
- GSM9307749 K27_A3_L1
- GSM9307750 K27_I1_L1
- GSM9307751 K27_I2_L1
- GSM9307752 K27_I3_L1
- GSM9307761 A1 A
- GSM9307762 A2 A
- GSM9307763 A3 A
- GSM9307764 I1 I
- GSM9307765 I2 I
- GSM9307766 I3 I
- GSE310734 Wnt-materials sustain H3K14-acetylation in human skeletal stem cells for tissue engineering and bone repair [CUT&Tag] 12 samples shares h3k14-acetylation, wnt-materials, engineering, skeletal, sustain, repair, stem, bone
- GSE310733 Wnt-materials sustain H3K14-acetylation in human skeletal stem cells for tissue engineering and bone repair [ATAC-Seq] 8 samples shares h3k14-acetylation, wnt-materials, engineering, skeletal, sustain, repair, stem, bone
- GSE234040 Human Skeletal Development and Regenerative Capacity is Shaped by Skeletal Stem Cell Diversity 39 samples shares skeletal, stem
- GSE263838 The interactive effect of sustained sleep restriction and resistance exercise on skeletal muscle transcriptomics in young females 38 samples shares skeletal, sustain
- GSE233970 Human Skeletal Stem Cell Diversity 34 samples shares skeletal, stem
- GSE318716 In vivo engineering of hematopoietic stem cells by targeted lipid nanoparticles within humanized mice 21 samples shares engineering, stem
- GSE275241 Genome engineering of primary and pluripotent stem cell-derived hepatocytes for modeling liver tumor formation 18 samples shares engineering, stem
- GSE288046 Modeling human limb skeletal development using human pluripotent stem cell-derived skeletal assembloids [CUT&Tag] 16 samples shares skeletal, stem
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.