IKAROS re-expression modulates transcriptional networks in IKZF1-mutant Ph+ B-ALL [ChIP-Seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 25 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 25 samples: 12 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- IKAROS Gene Regulatory Network Reveal ERG as a Vulnerability in B-cell Acute Lymphoblastic LeukemiabioRxiv : the preprint server for biology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE310890_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1367488 and SRA study SRP647451. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 24 samples.
How we read this: 12 replicated groups read from 25 sample titles; they account for 24 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9311399 ChIP-seq of IKAROS in MXP5 control rep1 ChIP-seq of IKAROS in M…
- GSM9311400 ChIP-seq of IKAROS in MXP5 control rep2 ChIP-seq of IKAROS in M…
- GSM9311401 ChIP-seq of IKAROS in MXP5 IK1 rep1 ChIP-seq of IKAROS in M…
- GSM9311402 ChIP-seq of IKAROS in MXP5 IK1 rep2 ChIP-seq of IKAROS in M…
- GSM9311403 ChIP-seq of ERG in MXP5 control rep1 ChIP-seq of ERG in MXP5…
- GSM9311404 ChIP-seq of ERG in MXP5 control rep2 ChIP-seq of ERG in MXP5…
- GSM9311405 ChIP-seq of ERG in MXP5 IK1 rep1 ChIP-seq of ERG in MXP5…
- GSM9311406 ChIP-seq of ERG in MXP5 IK1 rep2 ChIP-seq of ERG in MXP5…
- GSM9311407 ChIP-seq of CTCF in MXP5 control rep1 ChIP-seq of CTCF in MXP…
- GSM9311408 ChIP-seq of CTCF in MXP5 control rep2 ChIP-seq of CTCF in MXP…
- GSM9311409 ChIP-seq of CTCF in MXP5 IK1 rep1 ChIP-seq of CTCF in MXP…
- GSM9311410 ChIP-seq of CTCF in MXP5 IK1 rep2 ChIP-seq of CTCF in MXP…
- GSM9311411 ChIP-seq of H3K27ac in MXP5 control rep1 ChIP-seq of H3K27ac in …
- GSM9311412 ChIP-seq of H3K27ac in MXP5 control rep2 ChIP-seq of H3K27ac in …
- GSM9311413 ChIP-seq of H3K27ac in MXP5 IK1 rep1 ChIP-seq of H3K27ac in …
- GSM9311414 ChIP-seq of H3K27ac in MXP5 IK1 rep2 ChIP-seq of H3K27ac in …
- GSM9311415 ChIP-seq of H3K36me3 in MXP5 control rep1 ChIP-seq of H3K36me3 in…
- GSM9311416 ChIP-seq of H3K36me3 in MXP5 control rep2 ChIP-seq of H3K36me3 in…
- GSM9311417 ChIP-seq of H3K36me3 in MXP5 IK1 rep1 ChIP-seq of H3K36me3 in…
- GSM9311418 ChIP-seq of H3K36me3 in MXP5 IK1 rep2 ChIP-seq of H3K36me3 in…
- GSM9311419 ChIP-seq of H3K4me1 in MXP5 control rep1 ChIP-seq of H3K4me1 in …
- GSM9311420 ChIP-seq of H3K4me1 in MXP5 control rep2 ChIP-seq of H3K4me1 in …
- GSM9311421 ChIP-seq of H3K4me1 in MXP5 IK1 rep1 ChIP-seq of H3K4me1 in …
- GSM9311422 ChIP-seq of H3K4me1 in MXP5 IK1 rep2 ChIP-seq of H3K4me1 in …
- GSM9311423 Input for MXP5 ChIP-seq control rep1
- GSE310959 IKAROS re-expression modulates transcriptional networks in IKZF1-mutant Ph+ B-ALL [CUT&RUN] 14 samples shares ikaros, b-all, re-expression, ikzf1-mutant, modulates, networks
- GSE310887 IKAROS re-expression modulates transcriptional networks in IKZF1-mutant Ph+ B-ALL [ATAC-seq] 8 samples shares ikaros, b-all, re-expression, ikzf1-mutant, modulates, networks
- GSE310976 IKAROS re-expression modulates transcriptional networks in IKZF1-mutant Ph+ B-ALL 64 samples shares ikaros, b-all, re-expression, ikzf1-mutant, modulates, networks
- GSE310958 IKAROS re-expression modulates transcriptional networks in IKZF1-mutant Ph+ B-ALL [RNA-Seq] 13 samples shares ikaros, b-all, re-expression, ikzf1-mutant, modulates, networks
- GSE310891 IKAROS re-expression modulates transcriptional networks in IKZF1-mutant Ph+ B-ALL [HiChIP] 4 samples shares ikaros, b-all, re-expression, ikzf1-mutant, modulates, networks
- GSE301715 Mezigdomide reverses T cell exhaustion through degradation of Aiolos/Ikaros and reinvigoration of cytokine production pathways [ChIP-seq] 37 samples shares ikaros, chip-seq
- GSE225752 IKAROS modulates CD19 surface expression and CD19-directed CAR-T response [ATAC-seq] 12 samples shares ikaros, modulates
- GSE267437 Genome wide mapping of IKAROS binding (ChIP-Seq) in U-2932 cell line. 2 samples shares ikaros, chip-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.