Transcriptomic adaptations of human muscle in patients with polyarteritis nodosa and muscle denervation
RNA-seq (gene expression) · human · 13 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 13 samples: 8 × Muscle, Control, vs 5 × Muscle, PAN,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- A skeletal muscle atlas shows neuromuscular junction adaptations to growth and atrophyDevelopmental cell · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE311567_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1369877 and SRA study SRP649133. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 13 samples.
How we read this: 2 replicated groups read from 13 sample titles; they account for 13 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9327153 Muscle, PAN, rep1 Muscle, PAN,
- GSM9327154 Muscle, PAN, rep2 Muscle, PAN,
- GSM9327155 Muscle, PAN, rep3 Muscle, PAN,
- GSM9327156 Muscle, PAN, rep4 Muscle, PAN,
- GSM9327157 Muscle, PAN, rep5 Muscle, PAN,
- GSM9327158 Muscle, Control, rep1 Muscle, Control,
- GSM9327159 Muscle, Control, rep2 Muscle, Control,
- GSM9327160 Muscle, Control, rep3 Muscle, Control,
- GSM9327161 Muscle, Control, rep4 Muscle, Control,
- GSM9327162 Muscle, Control, rep5 Muscle, Control,
- GSM9327163 Muscle, Control, rep6 Muscle, Control,
- GSM9327164 Muscle, Control, rep7 Muscle, Control,
- GSM9327165 Muscle, Control, rep8 Muscle, Control,
- GSE312393 Transcriptomic adaptations of human muscle after short- and long-term exercise 13 samples shares adaptations, muscle
- GSE267512 Total testosterone is not associated with muscle mass, function or exercise adaptations in pre-menopausal females 57 samples shares adaptations, muscle
- GSE310878 Molecular phenotyping of diverse human skeletal muscles with CAGE-Seq 228 samples shares muscle
- GSE249921 Skeletal Muscle Transcriptome of Young and Old Humans and Response to Training 185 samples shares muscle
- GSE291383 Transcriptomic Profile of Skeletal Muscle Biopsies from Duchenne and Becker Muscular Dystrophy Patients 18 samples shares muscle
- GSE97084 Enhanced Protein Translation Underlies Improved Metabolic and Physical Adaptations to Different Exercise Training Modes in Young and Old Humans 103 samples shares adaptations
- GSE240766 SARS-CoV-2 infection of human pluripotent stem cell-derived vascular cells reveals smooth muscle cells as key mediators of vascular pathology during infection 101 samples shares muscle
- GSE329766 Transcriptomic profiling of BAZ1A-AS1 and BAZ1A knockdown in human vascular smooth muscle cells and rhabdomyoblasts 12 samples shares muscle
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.