GEO series
Peroxisomal ether lipid synthesis regulates cortical neurogenesis and maintains mitochondrial energy homeostasis in radial glial cells
GSE311937
Mus musculus
Expression profiling by high throughput sequencing
18 samples
2026/07/07
GPL24247
Summary
We demonstrate that peroxisomes undergo dynamic remodeling and display functional heterogeneity during neurogenesis. In human brain organoids and mouse models, peroxisome damage leads to mitochondrial dysfunction and inhibits the differentiation of radial glial cells.
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