Stag2-mediated chromatin dynamics regulates antibody class switch recombination
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 60 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 60 samples: 19 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Stag2-mediated chromatin dynamics regulates antibody class switch recombinationProceedings of the National Academy of Sciences of the United States of America · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE312233_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1372695 and SRA study SRP650766. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 59 samples.
How we read this: 19 replicated groups read from 60 sample titles; they account for 59 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9341030 IEM_3C_HTGTS_WT_rep1 IEM_3C_HTGTS_WT
- GSM9341031 IEM_3C_HTGTS_WT_rep2 IEM_3C_HTGTS_WT
- GSM9341032 IEM_3C_HTGTS_WT_rep3 IEM_3C_HTGTS_WT
- GSM9341033 IEM_3C_HTGTS_WT_rep4 IEM_3C_HTGTS_WT
- GSM9341034 IEM_3C_HTGTS_SA1_KO_rep1 IEM_3C_HTGTS_SA1_KO
- GSM9341035 IEM_3C_HTGTS_SA1_KO_rep2 IEM_3C_HTGTS_SA1_KO
- GSM9341036 IEM_3C_HTGTS_SA1_KO_rep3 IEM_3C_HTGTS_SA1_KO
- GSM9341037 IEM_3C_HTGTS_WT_rep5 IEM_3C_HTGTS_WT
- GSM9341038 IEM_3C_HTGTS_WT_rep6 IEM_3C_HTGTS_WT
- GSM9341039 IEM_3C_HTGTS_WT_rep7 IEM_3C_HTGTS_WT
- GSM9341040 IEM_3C_HTGTS_SA2_KO_rep1 IEM_3C_HTGTS_SA2_KO
- GSM9341041 IEM_3C_HTGTS_SA2_KO_rep2 IEM_3C_HTGTS_SA2_KO
- GSM9341042 IEM_3C_HTGTS_SA2_KO_rep3 IEM_3C_HTGTS_SA2_KO
- GSM9341117 5Su_CSR_HTGTS_WT_rep1 5Su_CSR_HTGTS_WT
- GSM9341119 5Su_CSR_HTGTS_WT_rep2 5Su_CSR_HTGTS_WT
- GSM9341121 5Su_CSR_HTGTS_WT_rep3 5Su_CSR_HTGTS_WT
- GSM9341123 5Su_CSR_HTGTS_SA1_KO_rep1 5Su_CSR_HTGTS_SA1_KO
- GSM9341124 5Su_CSR_HTGTS_SA1_KO_rep2 5Su_CSR_HTGTS_SA1_KO
- GSM9341126 5Su_CSR_HTGTS_SA1_KO_rep3 5Su_CSR_HTGTS_SA1_KO
- GSM9341128 5Su_CSR_HTGTS_WT_rep4 5Su_CSR_HTGTS_WT
- GSM9341130 5Su_CSR_HTGTS_WT_rep5 5Su_CSR_HTGTS_WT
- GSM9341132 5Su_CSR_HTGTS_WT_rep6 5Su_CSR_HTGTS_WT
- GSM9341133 5Su_CSR_HTGTS_SA2_KO_rep1 5Su_CSR_HTGTS_SA2_KO
- GSM9341135 5Su_CSR_HTGTS_SA2_KO_rep2 5Su_CSR_HTGTS_SA2_KO
- GSM9341137 5Su_CSR_HTGTS_SA2_KO_rep3 5Su_CSR_HTGTS_SA2_KO
- GSM9341280 RAD21_ChIPseq_WT_rep1 RAD21_ChIPseq_WT
- GSM9341282 RAD21_ChIPseq_WT_rep2 RAD21_ChIPseq_WT
- GSM9341284 RAD21_ChIPseq_SA1_KO_rep1 RAD21_ChIPseq_SA1_KO
- GSM9341285 RAD21_ChIPseq_SA1_KO_rep2 RAD21_ChIPseq_SA1_KO
- GSM9341287 RAD21_ChIPseq_WT_rep3 RAD21_ChIPseq_WT
- GSM9341289 RAD21_ChIPseq_WT_rep4 RAD21_ChIPseq_WT
- GSM9341291 RAD21_ChIPseq_SA2_KO_rep1 RAD21_ChIPseq_SA2_KO
- GSM9341292 RAD21_ChIPseq_SA2_KO_rep2 RAD21_ChIPseq_SA2_KO
- GSM9341294 STAG2_ChIPseq_WT_rep1 STAG2_ChIPseq_WT
- GSM9341296 STAG2_ChIPseq_WT_rep2 STAG2_ChIPseq_WT
- GSM9341298 STAG2_ChIPseq_SA1_KO_rep1 STAG2_ChIPseq_SA1_KO
- GSM9341299 STAG2_ChIPseq_SA1_KO_rep2 STAG2_ChIPseq_SA1_KO
- GSM9341301 STAG1_ChIPseq_WT_rep1 STAG1_ChIPseq_WT
- GSM9341303 STAG1_ChIPseq_WT_rep2 STAG1_ChIPseq_WT
- GSM9341305 STAG1_ChIPseq_SA2_KO_rep1 STAG1_ChIPseq_SA2_KO
+ 20 more — browse all 60 samples with per-sample file links →
- GSE264193 H3K27 dimethylation dynamics reveal stepwise establishment of facultative heterochromatin in early mouse embryos [ChIP-seq] 57 samples shares chromatin, dynamics
- GSE306869 The RNA binding protein LIN28A mediates chromatin dynamics during neuronal differentiation 24 samples shares chromatin, dynamics
- GSE320350 Nuclear class 3 PI3K co-activates fasting-specific chromatin remodeling 12 samples shares chromatin, class
- GSE296815 Polycomb Chromatin Topology Enables Long-Range Enhancer Recruitment during Craniofacial Development 98 samples shares chromatin
- GSE331488 A global view of cell-type-specific temporal dynamics in mammalian aging [I] 771 samples shares dynamics
- GSE331489 A global view of cell-type-specific temporal dynamics in mammalian aging [II] 725 samples shares dynamics
- GSE72539 CTCF binding polarity determines chromatin looping [4C] 504 samples shares chromatin
- GSE166225 Inference of emergent spatio-temporal processes from single-cell sequencing reveals feedback between de novo DNA methylation and chromatin condensates [RNA-seq] 288 samples shares chromatin
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.