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RNAseq comparison of Alkbh5 knockout AT2 cells

GSE312245 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2026/04/29 Platform GPL24247
Summary
We performed RNA sequencing on FACS-purified alveolar type II (AT2) cells isolated from Alkbh5 conditional knockout mice and littermate controls. AT2 cells were collected 14 days after bleomycin-induced lung injury. The dataset captures transcriptional changes associated with Alkbh5 deletion in AT2 cells, including the observed upregulation of Amphiregulin (Areg). These data provide a resource for analyzing gene expression programs in regenerating alveolar epithelium.
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Direct links to NCBI, no account and no request form: the whole study as GSE312245_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1372718 and SRA study SRP650790. Searching any of these in the dataset finder brings you back here.

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