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Postnatal day 3 (P3) mouse cortical projection neurons: Ctrl versus Cdk7 KO

GSE314177 Mus musculus (mouse) RNA-seq (gene expression) 10 samples Submitted 2026/07/15 Platform GPL24247
At a glance

RNA-seq (gene expression) · mouse · 10 samples

What it is
RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
Organism
Mus musculus (mouse)
Samples
10 samples
Data you can get
A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Paper
Cdk7 promotes neuritogenesis in cortical neurons and contributes to social behavior in miceCellular and molecular life sciences : CMLS · 2026
Summary (written by the submitters)
Transcriptional profiling of primary Cdk7 KO mouse cortical projection neurons compared to Ctrl neurons. Samples were obtained by FACS sorting EYFP+ cells from postnatal day 3 (P3) NexCre/+;Cdk7lox/lox, R26EYFP/+ (Cdk7 KO) and NexCre/+;Cdk7+/+, R26EYFP/+ (Ctrl) mouse cortices. Goal was to determine the effects of Cdk7 elimination on gene transcription in developing cortical projection neurons.
Published in
Cdk7 promotes neuritogenesis in cortical neurons and contributes to social behavior in mice
Verteneuil S, Van Hees L, Lassance JM et al. · Cellular and molecular life sciences : CMLS 2026 · PMID 42154236 · doi:10.1007/s00018-026-06139-8
This dataset
Download · which file do I need?

Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE314177_RAW.tar (it can run to tens of gigabytes).

3 · Start from the raw reads

Raw sequencing reads

The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.

What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.

Also filed as BioProject PRJNA1390211 and SRA study SRP656052. Searching any of these in the dataset finder brings you back here.

Samples in this study

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+ 10 more — browse all 10 samples with per-sample file links →

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