RNA-seq analysis of PAPD5 inhibitor effects in expanded human induced pluripotent stem cell-derived cardiomyocytes
RNA-seq (gene expression) · human · 13 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 13 samples: 5 × E-CM vs 3 × N-CM vs 3 × E-CM-B vs 2 × N-CM-BGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Senescence modulated cardiac repair with pluripotent stem cell-derived cardiomyocytesStem cell research & therapy · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE314271_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1390643 and SRA study SRP656367. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 13 samples.
How we read this: 4 replicated groups read from 13 sample titles; they account for 13 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9391985 N-CM1 N-CM
- GSM9391986 N-CM2 N-CM
- GSM9391987 N-CM3 N-CM
- GSM9391988 E-CM1 E-CM
- GSM9391989 E-CM2 E-CM
- GSM9391990 E-CM3 E-CM
- GSM9391991 E-CM-B1 E-CM-B
- GSM9391992 E-CM-B2 E-CM-B
- GSM9391993 E-CM-B3 E-CM-B
- GSM9391994 E-CM-R1 E-CM
- GSM9391995 E-CM-R2 E-CM
- GSM9391996 N-CM-B1 N-CM-B
- GSM9391997 N-CM-B2 N-CM-B
- GSE262419 Informing Hazard Identification and Risk Characterization of Environmental Chemicals by Combining Transcriptomic and Functional Data from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes 4558 samples shares cardiomyocytes, cell-derived, pluripotent, induced
- GSE293391 Healthy human induced pluripotent stem cell-derived cardiomyocytes exhibit sex dimorphism even without the addition of hormones 18 samples shares cardiomyocytes, cell-derived, pluripotent, induced
- GSE332763 Studying the effect of sarcomeric MYH7R663H and non-sarcomeric BRAFT599R hypertrophic cardimyopathy mutations in human induced pluripotent stemm cell-derived cardiomyocytes 15 samples shares cardiomyocytes, cell-derived, pluripotent, induced
- GSE255982 Persistent epigenome anomalies in induced pluripotent stem cells from late-onset sporadic Alzheimer’s disease cases [RNA-seq] 52 samples shares pluripotent, rna-seq, induced
- GSE249826 Human-induced pluripotent Stem Cell-Derived Hepatic Stellate Cells in Liver Organoids: Maturation Promotion and Essential Role in Vascularization 26 samples shares cell-derived, pluripotent, induced
- GSE268981 Graphene-polymer nanofibers enable optically induced electrical maturation in stem cell-derived cardiomyocytes and brain organoids 23 samples shares cardiomyocytes, cell-derived, induced
- GSE283726 Induced pluripotent stem cell-derived mesenchymal stem cells (iMSCs) inhibit M1 macrophage polarization and reduce alveolar bone loss associated with periodontitis 16 samples shares cell-derived, pluripotent, induced
- GSE226477 Bulk RNA-seq of neuromuscular system models generated from human induced pluripotent stem cells (hiPSCs) 15 samples shares pluripotent, rna-seq, induced
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.