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Integrated long- and short-read transcriptomics define TRP channel expression in adult mouse cortex

GSE315051 Mus musculus Expression profiling by high throughput sequencing 7 samples Submitted 2026/04/10 Platform GPL26624Platform GPL24247Platform GPL24973
Summary
Transient receptor potential (TRP) ion channels are polymodal cation channels with well-established roles in peripheral sensory systems, whereas their expression landscape in the adult cerebral cortex remains incompletely defined. This study provides integrated Oxford Nanopore direct RNA sequencing and Illumina RNA-seq datasets from adult mouse cortex, together with Illumina RNA-seq of dorsal root ganglia as a peripheral sensory reference. Three independent cortical biological replicates were profiled on both platforms. These datasets enable quantitative analysis of TRP channel gene- and isoform-level expression, cross-platform comparison of transcript abundance, and full-length transcript characterisation using long-read sequencing aligned to the Ensembl GRCm39 release 115 reference genome. Raw sequencing files and processed gene- and transcript-level expression tables are provided as a resource for transcriptomic analysis of adult mouse neural tissues.
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Direct links to NCBI, no account and no request form: the whole study as GSE315051_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 7 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1394928 and SRA study SRP658438. Searching any of these in the dataset finder brings you back here.

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