Enhanced mitophagy promotes lung repair and regeneration by restoring epithelial metabolic fitness [RNA-Seq]
RNA-seq (gene expression) · mouse · 16 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 16 samples: 5 × AT2_RFP_wt_bleo vs 5 × AT2_RFP_u30_bleo vs 3 × AT2_RFP_wt_saline vs 3 × AT2_RFP_u30_salineGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Mitophagy promotes lung repair and regeneration by restoring epithelial metabolic fitnessNature communications · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE317252_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1406628 and SRA study SRP665553. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 4 replicated groups read from 16 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9468029 AT2_RFP_wt_saline_1 AT2_RFP_wt_saline
- GSM9468030 AT2_RFP_wt_saline_2 AT2_RFP_wt_saline
- GSM9468031 AT2_RFP_wt_saline_3 AT2_RFP_wt_saline
- GSM9468032 AT2_RFP_wt_bleo_1 AT2_RFP_wt_bleo
- GSM9468033 AT2_RFP_wt_bleo_2 AT2_RFP_wt_bleo
- GSM9468034 AT2_RFP_wt_bleo_3 AT2_RFP_wt_bleo
- GSM9468035 AT2_RFP_wt_bleo_4 AT2_RFP_wt_bleo
- GSM9468036 AT2_RFP_wt_bleo_5 AT2_RFP_wt_bleo
- GSM9468037 AT2_RFP_u30_saline_1 AT2_RFP_u30_saline
- GSM9468038 AT2_RFP_u30_saline_2 AT2_RFP_u30_saline
- GSM9468039 AT2_RFP_u30_saline_3 AT2_RFP_u30_saline
- GSM9468040 AT2_RFP_u30_bleo_1 AT2_RFP_u30_bleo
- GSM9468041 AT2_RFP_u30_bleo_2 AT2_RFP_u30_bleo
- GSM9468042 AT2_RFP_u30_bleo_3 AT2_RFP_u30_bleo
- GSM9468043 AT2_RFP_u30_bleo_4 AT2_RFP_u30_bleo
- GSM9468044 AT2_RFP_u30_bleo_5 AT2_RFP_u30_bleo
- GSE326641 Ubiquitin-like proteins NEDD8 and SUMO2 control epithelial homeostasis, regeneration, and inflammation [scRNA-seq] 8 samples shares regeneration, epithelial, rna-seq
- GSE342447 TH-positive pulmonary nerve fiber-epithelial interaction promotes adipose thermogenesis in male mice [C22_RNA-seq] 4 samples shares epithelial, promotes, rna-seq
- GSE307773 Oncogenic MAPK signalling induces epithelial cell state change and therapeutic resistance in vivo [RNA-Seq] 175 samples shares epithelial, rna-seq
- GSE226579 Stem Cell Activity-Coupled Suppression of Endogenous Retrovirus Governs Adult Tissue Regeneration [RNA-seq] 47 samples shares regeneration, rna-seq
- GSE205410 Multiple subpopulations in medullary thymic epithelial cells are regulated by Aire with distinctive modes of gene regulations [bulkRNA-seq] 47 samples shares epithelial, rna-seq
- GSE248585 A conserved epithelial wound-like transcriptional program driven by FOSL1 underlies malignant progression of pancreatic ductal adenocarcinoma (ssRNA-Seq) 46 samples shares epithelial, rna-seq
- GSE267936 Functional Optic Tract Rewiring via Subtype- and Target-specific Axonal Regeneration and Presynaptic Activity Enhancement (bulk RNA-Seq) 40 samples shares regeneration, rna-seq
- GSE300722 Organoid modeling of lung branching morphogenesis and epithelial lineage specification [RNA-Seq] 40 samples shares epithelial, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.