GEO series
Degradation of perineuronal nets in hippocampal CA2 explains the loss of social cognition memory in Alzheimer's disease
GSE317499
Mus musculus
Expression profiling by high throughput sequencing
16 samples
2026/01/28
GPL24247
Summary
Loss of social cognition memory impairs Alzheimer's disease (AD) patients to recognize family members, friends, and caregivers. We investigate the role of perineuronal nets (PNNs), specialized coats of extracellular matrix around hippocampal CA2 neurons in AD‐associated social memory impairments.
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Paper (PMID 41122803) ↗
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