GEO series
Aldehyde dehydrogenase 2 deficiency exacerbates alcohol-associated liver fibrosis
GSE317551
Mus musculus
Expression profiling by high throughput sequencing
15 samples
2026/07/05
GPL24247
Summary
This study investigates the role of Aldehyde Dehydrogenase 2 (ALDH2) in the pathogenesis of liver fibrosis. We performed gene expression profiling of liver tissues from wild-type (WT) and Aldh2 knockout mice subjected to a chronic fibrosis model. This dataset aims to identify molecular mechanisms and transcriptomic alterations associated with ALDH2 deficiency in the context of alcohol- and CCl4-induced liver fibrosis.
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