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scRNA-seq of murine oropharyngeal carcinoma

GSE318632 Mus musculus Expression profiling by high throughput sequencing; Other 8 samples Submitted 2026/04/17 Platform GPL24247
Summary
We performed scRNA-seq analysis using the 10X genomics platform of mice following injection of mouse oropharyngeal carcinoma cell line MOPC in the flank of C57BL6/J to generate a model of murine oropharyngeal carcinoma. Here, we isolated bone marrow, spleen, blood and tumor from Gr1+and cKit+-enriched cells to investigate the dynamics of production across both sites of origin.
Published in
Divergent granulopoiesis at extramedullary sites safeguards antibacterial host defense
Silvestre-Roig C, Chevre R, Farjia M et al. · Science immunology 2026 · PMID 41996475 · doi:10.1126/sciimmunol.adw7077
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Direct links to NCBI, no account and no request form: the whole study as GSE318632_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1419608 and SRA study SRP675135. Searching any of these in the dataset finder brings you back here.

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