Vascular STING activation facilitates NK cell anti-tumor immunity in small cell lung cancer
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 16 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Topic
- Small cell lung cancerThis series is part of our curated briefing on it.
- Samples
- 16 samples: 14 distinct titles, 2 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Vascular STING activation facilitates NK cell anti-tumor immunity in small cell lung cancerCancer cell · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE318663_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1419736 and SRA study SRP674628. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 16 sample titles: 14 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9485941 H69_Parental
- GSM9485942 H69EZ_HLA_Negative
- GSM9485943 H69EZ_HLA_Positive
- GSM9485944 H69GV_HLA_Negative
- GSM9485945 H69GV_HLA_Positive
- GSM9492103 H69EZ-GV HLA negative 1
- GSM9492104 H69EZ-GV HLA negative 2
- GSM9492105 H69EZ-GV HLA positive 1
- GSM9492106 H69EZ-GV HLA positive 2
- GSM9494010 DynaMITE-control
- GSM9494011 DynaMITE-cGAMP
- GSM9494012 DynaMITE-control-monocyte
- GSM9494013 DynaMITE-cGAMP-monocyte
- GSM9505080 VA1_SCLC
- GSM9505081 VB1_SCLC
- GSM9505082 VA2_SCLC
- GSE244947 NOTCH1 reverses immune suppression in small cell lung cancer through reactivation of STING 87 samples same disease briefing · shares sting, activation, small, lung
- GSE289452 ABL Kinase Inactivation Promotes Transcription-Replication Conflicts and Compromises Replication Forks Revealing a Therapeutic Vulnerability in Metastatic Small Cell Lung Cancer 6 samples same disease briefing · shares activation, small, lung
- GSE249362 Non-Canonical BAF and mSWI/SNF Regulates POU2F3 and are Selective Targetable Dependencies for POU2F3-Positive Small Cell Lung Cancer 125 samples same disease briefing · shares small, lung
- GSE244123 Olfactory neuroblastoma mimics molecular subtypes and lineage trajectories of small cell lung cancer 103 samples same disease briefing · shares small, lung
- GSE208446 Small cell lung cancer responds to inhibition of Jumonji enzyme in vitro and in vivo 90 samples same disease briefing · shares small, lung
- GSE255095 An in vivo screening platform using PDX models reveals KEAP1, USP22 and other drivers of chemoresistance in small cell lung cancer 67 samples same disease briefing · shares small, lung
- GSE281525 RNA-sequence data of clinically never-metastatic primary small cell lung cancer cases and small cell lung cancer metastasis cases, FOXA2 knock-down and overexpression in cell lines 61 samples same disease briefing · shares small, lung
- GSE262597 EIF6 conditions drug-tolerant persister-like transdifferentiation in small cell lung carcinoma 56 samples same disease briefing · shares small, lung
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.