Astrocyte Reactivity by Alcohol Dependence in the Central Amygdala
RNA-seq (gene expression) · mouse · 97 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 97 samples: 97 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Astrocyte reactivity by alcohol dependence in the central amygdalaBrain, behavior, and immunity · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE325031_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1438265 and SRA study SRP684257. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 97 sample titles: 97 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9594103 CeA, E01, Female, Non-Dependent, Input
- GSM9594104 CeA, E01, Female, Non-Dependent, IP
- GSM9594105 CeA, E02, Female, Dependent, Input
- GSM9594106 CeA, E02, Female, Dependent, IP
- GSM9594107 CeA, E03, Male, Non-Dependent, Input
- GSM9594108 CeA, E03, Male, Non-Dependent, IP
- GSM9594109 CeA, E04, Female, Non-Dependent, Input
- GSM9594110 CeA, E04, Female, Non-Dependent, IP
- GSM9594111 CeA, E05, Female, Dependent, Input
- GSM9594112 CeA, E05, Female, Dependent, IP
- GSM9594113 CeA, E06, Male, Non-Dependent, Input
- GSM9594114 CeA, E06, Male, Non-Dependent, IP
- GSM9594115 CeA, E07, Male, Dependent, Input
- GSM9594116 CeA, E07, Male, Dependent, IP
- GSM9594117 CeA, E08, Female, Non-Dependent, Input
- GSM9594118 CeA, E08, Female, Non-Dependent, IP
- GSM9594119 CeA, E09, Female, Dependent, Input
- GSM9594120 CeA, E09, Female, Dependent, IP
- GSM9594121 CeA, E10, Male, Non-Dependent, Input
- GSM9594122 CeA, E10, Male, Non-Dependent, IP
- GSM9594123 CeA, E11, Male, Dependent, Input
- GSM9594124 CeA, E11, Male, Dependent, IP
- GSM9594125 CeA, E12, Female, Non-Dependent, Input
- GSM9594126 CeA, E12, Female, Non-Dependent, IP
- GSM9594127 CeA, E13, Female, Dependent, Input
- GSM9594128 CeA, E13, Female, Dependent, IP
- GSM9594129 CeA, E14, Male, Non-Dependent, IP
- GSM9594130 CeA, E15, Male, Dependent, Input
- GSM9594131 CeA, E15, Male, Dependent, IP
- GSM9594132 CeA, E16, Female, Non-Dependent, Input
- GSM9594133 CeA, E16, Female, Non-Dependent, IP
- GSM9594134 CeA, F01, Female, Naive, Input
- GSM9594135 CeA, F01, Female, Naive, IP
- GSM9594136 CeA, F02, Male, Naive, Input
- GSM9594137 CeA, F02, Male, Naive, IP
- GSM9594138 CeA, F03, Male, Non-Dependent, Input
- GSM9594139 CeA, F03, Male, Non-Dependent, IP
- GSM9594140 CeA, F04, Female, Non-Dependent, Input
- GSM9594141 CeA, F04, Female, Non-Dependent, IP
- GSM9594142 CeA, F05, Male, Dependent, Input
+ 57 more — browse all 97 samples with per-sample file links →
- GSE308880 Alcohol Dependence-Induced Astrocyte Immune Activation in the Nucleus Accumbens 95 samples shares dependence, astrocyte, alcohol
- GSE288772 Genomic and Behavioral Signatures of Selection for Ethanol Preference from the Heterogeneous Stock Collaborative Cross Mice – The Central Nucleus of the Amygdala 200 samples shares amygdala, central
- GSE272272 Changes in the astrocyte translatome induced by developmental ethanol mediate dysregulation of neuronal development: role of the extracellular matrix and relevance to Fetal Alcohol Spectrum Disorders 48 samples shares astrocyte, alcohol
- GSE293026 REV-ERB-alpha and -beta coordinately regulate astrocyte reactivity and proteostatic function 26 samples shares reactivity, astrocyte
- GSE294133 CLU alleviates Alzheimer’s disease-relevant processes by modulating astrocyte reactivity and microglia-dependent synaptic density [RNA-Seq] 19 samples shares reactivity, astrocyte
- GSE248275 Adenosine triggers early astrocyte reactivity that provokes microglial reaction and drives the pathogenesis of sepsis-associated encephalopathy 18 samples shares reactivity, astrocyte
- GSE326801 Astrocyte-microglia crosstalk via CSF1 and IFNb promotes central nervous system repair 14 samples shares astrocyte, central
- GSE326646 Astrocyte molecular changes during basolateral amygdala-related emotional behaviors [set8] 12 samples shares astrocyte, amygdala
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.