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Genome-wide binding of ZFPOBI1/TRIM28 and linked H3K9me3 dynamics

GSE326899 Mus musculus (mouse) ChIP-seq / ATAC-seq (genome binding and open chromatin) 20 samples Submitted 2026/07/31 Platform GPL19057
At a glance

ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 20 samples

What it is
ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
Organism
Mus musculus (mouse)
Samples
20 samples: 6 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
Data you can get
A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Summary (written by the submitters)
This work describes the function and targets of a maternal KRAB-Zinc finger protein, ZFPOBI1, which specifically targets a subset of LTR retrotransposons during embryonic epigenetic reprogramming.
This dataset
Download · which file do I need?

Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE326899_RAW.tar (it can run to tens of gigabytes).

3 · Start from the raw reads

Raw sequencing reads

The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.

What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.

Also filed as BioProject PRJNA1447576 and SRA study SRP689008. Searching any of these in the dataset finder brings you back here.

Study design
6 conditions, mostly in triplicate
vector control HA-ChIP ×3 vector control TRIM28-ChIP ×3 vector control H3K9me3_ChIP ×3 HA-ZFPOBI1 OE HA-ChIP ×3 HA-ZFPOBI1 OE TRIM28-ChIP ×3 HA-ZFPOBI1 OE H3K9me3_ChIP ×3 vector control INPUT ×1 HA-ZFPOBI1 OE INPUT ×1

Supports a between-group comparison across 18 samples.

How we read this: 6 replicated groups read from 20 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.

Samples in this study
Datasets on a similar topic

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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.