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Transcriptome analysis of ureter tissues from wild-type and COL17 knockout mice.

GSE327077 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2026/04/16 Platform GPL34290
Summary
Type XVII collagen (COL17A1) is well-characterized as a critical structural component of the epidermal basement membrane in the skin; however, its presence and function in the urinary tract remain poorly described. We discovered that COL17A1 is also expressed in the urothelium under urological condition. To elucidate the molecular mechanisms underlying early urothelial abnormalities caused by COL17A1 deficiency, we performed transcriptomic profiling (bulk RNA-seq) of ureter tissues from 2-week-old wild-type and Col17a1 knockout mice.
Published in
Morphological abnormalities in the ureter of type XVII collagen-deficient mice
Suzui A, Namba T, Hiraishi M et al. · Scientific reports 2026 · PMID 42045289 · doi:10.1038/s41598-026-49868-3
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Also filed as BioProject PRJNA1449414 and SRA study SRP689534. Searching any of these in the dataset finder brings you back here.

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