Choroid plexus inflammation in bipolar disorder
RNA-seq (gene expression) · human · 23 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 23 samples: 23 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Choroid plexus inflammation in bipolar disorderBrain, behavior, and immunity · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE328018_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1453522 and SRA study SRP691817. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 23 sample titles: 23 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9670410 S1_ChP_Ctrl
- GSM9670411 S2_ChP_Ctrl
- GSM9670412 S3_ChP_BD
- GSM9670413 S4_ChP_BD
- GSM9670414 S5_ChP_Ctrl
- GSM9670415 S6_ChP_BD
- GSM9670416 S7_ChP_Ctrl
- GSM9670417 S8_ChP_Ctrl
- GSM9670418 S9_ChP_Ctrl
- GSM9670419 S10_ChP_Ctrl
- GSM9670420 S11_ChP_BD
- GSM9670421 S12_ChP_Ctrl
- GSM9670422 S13_ChP_Ctrl
- GSM9670423 S14_ChP_BD
- GSM9670424 S15_ChP_Ctrl
- GSM9670425 S16_ChP_BD
- GSM9670426 S17_ChP_Ctrl
- GSM9670427 S18_ChP_BD
- GSM9670428 S19_ChP_Ctrl
- GSM9670429 S20_ChP_BD
- GSM9670430 S21_ChP_BD
- GSM9670431 S22_ChP_BD
- GSM9670432 S23_ChP_Ctrl
- GSE306819 Single-nucleus RNA sequencing in the post-mortem thamaus and cortex in bipolar disorder 82 samples shares disorder, bipolar
- GSE236482 Molecular signatures of hyperexcitability and lithium responsiveness in bipolar disorder patient neurons provides alternative therapeutic strategies 28 samples shares disorder, bipolar
- GSE272060 Human-Induced Pluripotent Stem Cell (iPSC)-Derived GABAergic Neuron Differentiation in Bipolar Disorder 21 samples shares disorder, bipolar
- GSE264154 Single Nucleus RNAseq dissection of choroid plexus tumor cell heterogeneity 15 samples shares choroid, plexus
- GSE316497 Genotype-Epigenome-Phenotype Integration Reveals the Contributions of Peripheral Immune Cells to Bipolar Disorder Pathogenesis, Phenotypic Heterogeneity, and Therapy 1012 samples shares disorder, bipolar
- GSE263845 Transcriptomic and epigenomic consequences of heterozygous loss-of-function mutations in AKAP11, a shared risk gene for bipolar disorder and schizophrenia [ChIP-seq] 10 samples shares disorder, bipolar
- GSE213380 Acamprosate, Craving and Alcohol Use Disorder: the Role of Inflammation 48 samples shares disorder
- GSE262138 Convergent transcriptomic signatures across brain structures in eating disorders and obsessive compulsive disorder 338 samples shares disorder
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.