GEO series
Choroid plexus inflammation in bipolar disorder
GSE328018
Homo sapiens
Expression profiling by high throughput sequencing
23 samples
2026/06/18
GPL34281
Summary
Postmortem human choroid plexus tissue from individuals with bipolar disorder and matched controls was analyzed using cytokine protein arrays and bulk RNA sequencing to characterize immune and barrier-related alterations. The study identifies increased pro-inflammatory signaling and reduced trophic/supportive pathways, implicating the choroid plexus as a neuroimmune interface in bipolar disorder.
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Paper (PMID 41980683) ↗
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