Long-term maintenance of H3K27me3 in postmitotic neurons is dispensable for gene expression regulation
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 44 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 44 samples: 12 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE329815_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1461876 and SRA study SRP695614. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 32 samples.
How we read this: 12 replicated groups read from 44 sample titles; they account for 32 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9701787 Cortex, WT, rep1 Cortex, WT,
- GSM9701788 Cortex, WT, rep2 Cortex, WT,
- GSM9701789 Cortex, WT, rep3 Cortex, WT,
- GSM9701790 Cortex, WT, rep4 Cortex, WT,
- GSM9701791 Cortex, Ezh1cKO, rep1 Cortex, Ezh1cKO,
- GSM9701792 Cortex, Ezh1cKO, rep2 Cortex, Ezh1cKO,
- GSM9701793 Cortex, Ezh1cKO, rep3 Cortex, Ezh1cKO,
- GSM9701794 Cortex, Ezh1cKO, rep4 Cortex, Ezh1cKO,
- GSM9705183 GCP, P7, 5hmC
- GSM9705184 GCP, P7, 5mC
- GSM9705185 GC, P21, 5hmC
- GSM9705186 GC, P21, 5mC
- GSM9719126 GCP, P5, rep1 GCP, P5,
- GSM9719127 GCP, P5, rep2 GCP, P5,
- GSM9719128 GC, P21, rep1 GC, P21,
- GSM9719129 GC, P21, rep2 GC, P21,
- GSM9719130 GC, 7m, WT, rep1 GC, 7m, WT,
- GSM9719131 GC, 7m, WT, rep2 GC, 7m, WT,
- GSM9719132 GC, 7m, WT, rep3 GC, 7m, WT,
- GSM9719133 GC, 7m, Ezh1cKO, rep1 GC, 7m, Ezh1cKO,
- GSM9719134 GC, 7m, Ezh1cKO, rep2 GC, 7m, Ezh1cKO,
- GSM9719135 GC, 7m, Ezh1cKO, rep3 GC, 7m, Ezh1cKO,
- GSM9722302 GCP, P7, H3K36me2 GCP, P7, H3K36me
- GSM9722303 GCP, P7, H3K36me3 GCP, P7, H3K36me
- GSM9722304 GCP, P7, H3K9me3
- GSM9722305 GCP, P7, H3K27ac
- GSM9722306 GCP, P7, input for H3K36me2 GCP, P7, input for H3K3…
- GSM9722307 GCP, P7, input for H3K36me3 GCP, P7, input for H3K3…
- GSM9722308 GCP, P7, input for H3K9me3
- GSM9722309 GCP, P7, input for H3K27ac
- GSM9722310 GC, P21, H3K36me2 GC, P21, H3K36me
- GSM9722311 GC, P21, H3K36me3 GC, P21, H3K36me
- GSM9722312 GC, P21, H3K9me3
- GSM9722313 GC, P21, H3K27ac
- GSM9722314 GC, P21, input for H3K36me2 GC, P21, input for H3K3…
- GSM9722315 GC, P21, input for H3K36me3 GC, P21, input for H3K3…
- GSM9722316 GC, P21, input for H3K9me3
- GSM9722317 GC, P21, input for H3K27ac
- GSM9736894 GC, 7m, WT, nRNAseq, rep1 GC, 7m, WT, nRNAseq,
- GSM9736895 GC, 7m, WT, nRNAseq, rep2 GC, 7m, WT, nRNAseq,
+ 4 more — browse all 44 samples with per-sample file links →
- GSE330241 Long-term maintenance of H3K27me3 in postmitotic neurons is dispensable for gene expression regulation [ChIP-Seq] 16 samples shares h3k27me3, maintenance, postmitotic, dispensable, long-term, neurons
- GSE190102 Ageing-Related Changes to H3K4me3, H3K27ac and H3K27me3 in Purified Mouse Neurons 43 samples shares h3k27me3, neurons
- GSE225240 Reevaluation by CRISPR-Cas9 approach reveals multiple lincRNAs dispensable for pluripotency maintenance and SNORA73 essential for pluripotency exit 13 samples shares maintenance, dispensable
- GSE225237 Reevaluation by CRISPR-Cas9 approach reveals multiple lincRNAs dispensable for pluripotency maintenance and SNORA73 essential for pluripotency exit (RNA-Seq) 12 samples shares maintenance, dispensable
- GSE262390 Setd2 overexpression rescues bivalent gene expression during SCNT-mediated ZGA by enhancing H3K36me3 at gene bodies and excluding H3K27me3 from promoters [ChIP-seq] 79 samples shares h3k27me3
- GSE255571 Chromatin remodeler CHD7 regulates neurogenic gene expression via controlling chromatin accessibility and modifications of histone marks H3K27me3 and H3K4me3 [Mouse CUT&Tag] 10 samples shares h3k27me3
- GSE278811 EZHIP-mediated PRC2 inhibition is required to maintain H3K27me3-dependent imprinting post fertilization [ChIP-Seq] 77 samples shares h3k27me3
- GSE278534 EZHIP-mediated PRC2 inhibition is required to maintain H3K27me3-dependent imprinting post fertilization 76 samples shares h3k27me3
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.