GEO series
Impact of Peg3 deletion in mouse trophoblast stem cells on H3K9me3 profiles
GSE331039
Mus musculus
Genome binding/occupancy profiling by high throughput sequencing
12 samples
2026/06/19
GPL30172
Summary
Peg3 is an imprinted gene that in itself is a KRAB zinc finger protein. We established knockout trophoblast stem cell lines (TSCs) in which we ablated the majority of the zinc finger motifs of the PEG3 coding region using CRISPR-Cas9-mediated deletion. We then profiled wild-type (WT) and knockout (KO) TSC lines for the genome-wide distribution of the epigenetic repressive mark H3K9me3 by ChIP-seq.
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