GEO series
scRNAseq of LCMV-specific P14 cells: WT, P2RX7-KO and NKG7-KO
GSE337539
Mus musculus
Expression profiling by high throughput sequencing
8 samples
2026/07/08
GPL34290
Summary
We have used Parse Biosciences to generate single-cell RNAseq libraries from P14 CD8+ T cells (wild-type - WT, P2RX7-KO and NKG7-KO) collected from mice infected with either LCMV-Armstrong or LCMV-Clone 13 (days 0, 7 or 30 post-infection). The goal of this study was to determine the transcriptional alterations in memory or exhausted CD8+ T cells driven by the absence of either P2RX7 (a purinergic receptor that senses extracellular ATP) or NKG7 (a metabolic regulator that can downregulate mTORC1 and simultaneously induce cytotoxicity).
Download
NCBI GEO page ↗
{# Names what the click gives you. "Open in finder" meant nothing to a
visitor who arrived from a search engine and has never seen the tool. #}
Find more
mouse RNA-seq datasets →
Similar datasets
- GSE292862 Modelling mouse embryogenesis from chemically induced totipotent stem cells 22 samples
- GSE185862 A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation 95 samples
- GSE304862 Semaglutide and exercise synergy in obesity: preserving muscle mass and uncovering organ crosstalk 209 samples
- GSE293315 MRPGRX2 Antagonist Treatment Prevents Inflammation and Disease in a Mouse Model of Atopic Dermatitis Dataset 2 35 samples
- GSE255837 Dysregulation of the Normal Wound Healing Cascade in Volumetric Muscle Loss Injury 30 samples
- GSE341948 Multi-tissue transcriptomic landscape reveals synergistic mechanisms of exercise and GLP-1 agonist in ameliorating diabetic phenotypes in db/db mice 12 samples
- GSE337190 CAR-NKT cells induce low cytokine release syndrome by targeting hyperinflammatory macrophages with mitigation from GM-SCF inhibition. 24 samples
- GSE306116 Caspase-3 Control of RNA Splicing and Mitochondrial Dynamics in Microglia during Parkinson’s Disease [RNA-Seq] 12 samples
Share this dataset
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.