Single-cell RNA sequencing of murine hepatocellular carcinoma tumors following treatment with XG009, HCC010, or HCC010-D265A monoclonal antibodies
Single-cell RNA-seq · mouse · 9 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart.
- Organism
- Mus musculus (mouse)
- Samples
- 9 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE351109_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1544952 and SRA study SRP746462. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 9 more — browse all 9 samples with per-sample file links →
- GSE285359 Single-cell transcriptome landscape in hepatocellular carcinoma of BALB/C mice after azvudine treatment 12 samples shares hepatocellular, single-cell
- GSE330471 Single-cell transcriptomic profiling reveals that KLF2 limits tumor cell plasticity in hepatocellular carcinoma 4 samples shares hepatocellular, single-cell
- GSE270714 Precision targeting of beta-catenin induces tumor reprogramming and immunity in hepatocellular cancers [Single-cell RNA-seq GEX] 2 samples shares hepatocellular, single-cell
- GSE291594 Single-cell analysis of immune cell characteristics induced by Aoah over-expression in MYC-Luc spontaneous hepatocellular carcinoma tumors 24 samples shares hepatocellular, single-cell
- GSE301030 Inhibiting B-cell-mediated Immunosuppression to Enhance the Immunotherapy Efficacy in Hepatocellular Carcinoma 54 samples shares hepatocellular
- GSE302836 Loss of Hepatocyte PI3Ka Protects Mice from Hepatocellular Carcinoma in association with altered lipid metabolism gene expression 42 samples shares hepatocellular
- GSE303515 Sequential adaptive changes in a c-Myc-driven model of hepatocellular carcinoma 34 samples shares hepatocellular
- GSE230972 Loss of cisPTase function in the liver promotes a highly penetrant form of fatty liver disease that rapidly transitions to hepatocellular carcinoma 27 samples shares hepatocellular
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.