Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor
Expression microarray · mouse · 6 samples
- What it is
- Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
- Organism
- Mus musculus (mouse)
- Samples
- 6 samples: 2 × ileum.Sham_Vehicle vs 2 × ileum.BDL_Vehicle vs 2 × ileum.BDL_GW4064Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
Read the full summary ↓
Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need.
Whole study · RAW.tar
Everything the authors deposited as one archive (GSE40821_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.
What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.
Also filed as BioProject PRJNA175042. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 6 samples.
How we read this: 3 replicated groups read from 6 sample titles; they account for 6 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM1002554 ileum.Sham_Vehicle_rep-1 ileum.Sham_Vehicle
- GSM1002555 ileum.Sham_Vehicle_rep-2 ileum.Sham_Vehicle
- GSM1002556 ileum.BDL_Vehicle_rep-1 ileum.BDL_Vehicle
- GSM1002557 ileum.BDL_Vehicle_rep-2 ileum.BDL_Vehicle
- GSM1002558 ileum.BDL_GW4064_rep-1 ileum.BDL_GW4064
- GSM1002559 ileum.BDL_GW4064_rep-2 ileum.BDL_GW4064
- GSE314547 Estradiol disrupts constitutive androstane receptor (CAR)-mediated bile acid homeostasis in a murine model of intrahepatic cholestasis of pregnancy (ICP), and this effect is reversed by CAR ligands 16 samples shares receptor, bile, acid
- GSE309415 Bile acid receptor Tgr5 prevents macrophage hyperinflammation during bacterial sepsis through metabolic and epigenetic silencing 12 samples shares receptor, bile, acid
- GSE267452 Loss of Nuclear Receptor Nr4a3 Alleviates Cellular Senescence to Promote Adult Direct Cardiac Reprogramming 54 samples shares receptor, nuclear
- GSE326173 Nuclear receptor Nur77 resolves the inflammatory response of macrophages primarily by regulating expression of AP-1 transcription factors and their target genes [ChIP-seq] 42 samples shares receptor, nuclear
- GSE234065 Unexpected nuclear hormone receptor and chromatin dynamics regulate estrous cycle dependent gene expression 32 samples shares receptor, nuclear
- GSE294805 Effect of cardiomyocyte-specific activation of nuclear receptor subfamily 4 group A member 2 (NR4A2) on poly(A) RNA expression profile in the mouse heart [RNA-seq] 32 samples shares receptor, nuclear
- GSE325918 Nuclear receptor Nur77 resolves the inflammatory response of macrophages primarily by regulating expression of AP-1 transcription factors and their target genes [RNA-seq] 32 samples shares receptor, nuclear
- GSE317634 Negative regulation of TH17-mediated inflammation by the nuclear receptor REV-ERBβ 26 samples shares receptor, nuclear
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.