← BioTransfer GEO Dataset Finder
GEO series

Pdx1 maintains β-cell identity and function by repressing an α-cell program

GSE52258 Mus musculus Expression profiling by array 15 samples Submitted 2013/11/19 Platform GPL6246
Summary
To get a more complete picture of the transcriptional changes associated with Pdx1 loss in β-cells, we conducted an mRNA microarray comparing normal islet β-cells and a-cells to the reprogrammed cells from PKO mice. Islet beta cells are from mice which has a single copy of Pdx1 flox (Pdx1L/+) allele, but is considered normal based on normal islet morphology, gene profiling, and euglycemic status. We chose to use heterozygous mice as control to avoid the litter effect. Islet alpha cells are from normal mice.
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE52258_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 15 samples.

Also filed as BioProject PRJNA227298. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 15 more — browse all 15 samples with per-sample file links →

Similar datasets

Search all mouse microarray datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.