Gene expression and genotype data from human fibroblasts and induced Pluripotent Stem cells from Parkinson's Disease patients
Expression microarray · human · 14 samples
- What it is
- Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
- Organism
- Homo sapiens (human)
- Samples
- 14 samples: 4 × GBA-PD 1 iPSc clone vs 2 × GBA-PD 2 iPSc clone vs 2 × IDI-PD 1 iPSc clone vs 2 × IDI-PD 2 iPSc cloneGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need.
Whole study · RAW.tar
Everything the authors deposited as one archive (GSE53426_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.
What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.
Also filed as BioProject PRJNA231955. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
How we read this: 4 replicated groups read from 14 sample titles; they account for 10 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM1291200 GBA-PD 1 iPSc clone 1 GBA-PD 1 iPSc clone
- GSM1291201 GBA-PD 1 iPSc clone 3 GBA-PD 1 iPSc clone
- GSM1291202 GBA-PD 2 iPSc clone 1 GBA-PD 2 iPSc clone
- GSM1291203 IDI-PD 1 iPSc clone 3 IDI-PD 1 iPSc clone
- GSM1291204 IDI-PD 2 iPSc clone 3 IDI-PD 2 iPSc clone
- GSM1291205 GBA-PD 1 fibroblasts
- GSM1291206 GBA-PD 1 iPSc clone 1 GBA-PD 1 iPSc clone
- GSM1291207 GBA-PD 1 iPSc clone 3 GBA-PD 1 iPSc clone
- GSM1291208 GBA-PD 2 fibroblasts
- GSM1291209 GBA-PD 2 iPSc clone 1 GBA-PD 2 iPSc clone
- GSM1291210 IDI-PD 1 fibroblasts
- GSM1291211 IDI-PD 1 iPSc clone 3 IDI-PD 1 iPSc clone
- GSM1291212 IDI-PD 2 fibroblasts
- GSM1291213 IDI-PD 2 iPSc clone 3 IDI-PD 2 iPSc clone
- GSE324961 microRNA-132 attenuates inflammation in induced pluripotent stem-cell derived microglia from Alzheimer’s disease patients 95 samples shares pluripotent, induced, stem
- GSE255985 Persistent epigenome anomalies in induced pluripotent stem cells from late-onset sporadic Alzheimer’s disease cases 58 samples shares pluripotent, induced, stem
- GSE262710 Identifying SETBP1 haploinsufficiency molecular pathways to improve patient diagnosis using induced pluripotent stem cells and neural disease modelling. 46 samples shares pluripotent, induced, stem
- GSE253337 Mitochondrial anomalies in induced pluripotent stem cells from Alzheimer’s disease cases with Presenilin 1 mutation 36 samples shares pluripotent, induced, stem
- GSE266974 Eicosatetraynoic Acid Regulates Pro-Fibrotic Pathways in an Induced Pluripotent Stem Cell Derived Macrophage:Human Intestinal Organoid Model of Crohn’s Disease II 18 samples shares pluripotent, induced, stem
- GSE262419 Informing Hazard Identification and Risk Characterization of Environmental Chemicals by Combining Transcriptomic and Functional Data from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes 4558 samples shares pluripotent, induced, stem
- GSE226482 Single cell RNA sequencing of spinal motor neurons and interneurons differentiated from isogenic FUS and TARDBP human induced pluripotent stem cell lines harbouring ALS-causative mutations 1415 samples shares pluripotent, induced, stem
- GSE224698 Gene expression profiles of human dermal fibroblasts and human pluripotent stem cells analyzed by bulk RNA-seq 69 samples shares fibroblasts, pluripotent, stem
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.