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MicroArray Quality Control (MAQC) Project

GSE5350 Rattus norvegicus; Homo sapiens Expression profiling by array; Expression profiling by RT-PCR 943 samples Submitted 2006/09/08 Platform GPL1355Platform GPL4186Platform GPL2895Platform GPL4198Platform GPL4098Platform GPL1708Platform GPL2896Platform GPL2996Platform GPL4187Platform GPL2507Platform GPL4219Platform GPL4096Platform GPL4188Platform GPL2877Platform GPL4185Platform GPL4108Platform GPL570Platform GPL2986Platform GPL4097
Summary
Microarray technology has had a profound impact on gene expression research. Some studies have questioned whether similar expression results are obtained when the same RNA samples are analyzed on different platforms. The MicroArray Quality Control (MAQC) project was initiated to address these concerns, as well as other performance and analysis issues. We demonstrate the consistency of results within a platform across test sites as well as the high level of cross-platform concordance in terms of genes identified as differentially expressed. The MAQC study provides a rich resource that will help build consensus on the use of microarrays in research, clinical and regulatory settings. Manuscripts related to the MAQC project have been published in Nature Biotechnology, 24(9), September, 2006. More information about the MAQC project can be found at http://edkb.fda.gov/MAQC/. Keywords: Cross-platform comparison
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Also filed as BioProject PRJNA96213. Searching any of these in the dataset finder brings you back here.

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