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Analysis of Liver Progenitor Cells Generated from Yap Expression [Set 1]

GSE55558 Mus musculus Expression profiling by array 12 samples Submitted 2014/06/06 Platform GPL6246
Summary
Hippo signaling is highly associated with activity in the stem cell compartment of many epithelial tissues. In this study, we examined if Hippo signaling inhibition (by inducing Yap expression) could convert differentiated cells into a progenitor like phenotype. Organoid cells derived from mouse livers under various conditions, wild-type, Yap ON (Plus Dox), and Yap ON then OFF (Minus Dox) was examined. Comparison between freshly isolated hepatocytes; Uninduced_YPF-#.cel against Organoids grown in wild-type conditions (WT), Yap On (in vivo) off (in vitro) - YapOrganoidDoxMinus , and Yap On continuously - YapOrganoidDoxPlus.
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Also filed as BioProject PRJNA239960. Searching any of these in the dataset finder brings you back here.

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