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Analysis of Liver Progenitor Cells Generated from Yap Expression [Set 2]

GSE55559 Mus musculus Expression profiling by array; Third-party reanalysis 6 samples Submitted 2014/06/06 Platform GPL6246
Summary
Hippo signaling is highly associated with activity in the stem cell compartment of many epithelial tissues. In this study, we examined if Hippo signaling inhibition (by inducing Yap expression) could convert differentiated cells into a progenitor like phenotype. Rosa26-lsl-YFP mice had recombination induced and cells were FACS sorted using YFP as a marker at either 1 week or 6 weeks after recombination. YFP expression is a surrogate for Yap expression (our protein of interest) and time was varied in vivo. RNA was immediately extracted after sorting and labeled to be hybridized to the array.
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Also filed as BioProject PRJNA239958. Searching any of these in the dataset finder brings you back here.

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