GEO series

Transcriptomics and methylomics of human T cells [methylome]

GSE56581 Homo sapiens (human) DNA methylation 214 samples Submitted 2014/11/24 Platform GPL13534

At a glance

DNA methylation · human · 214 samples

What it is: DNA methylationChemical marks on DNA that help switch genes on or off.
Organism: Homo sapiens (human)
Samples: 214 samples
Data you can get: A processed table (series matrix) and supplementary files from NCBI.

Summary (written by the submitters)

The MESA Epigenomics and Transcriptomics Study has been launched to investigate potential gene expression regulatory methylation sites in humans by examining the association between CpG methylation and gene expression in purified human monocytes and T cells from a large study population (community-dwelling participants in the Multi-Ethnic Study of Atherosclerosis (MESA)). The MESA Epigenomics and Transcriptomics Study was funded by a National Heart, Lung and Blood Institute grant (R01HL101250) through the NIH Roadmap Epigenomics Program in 2009.

This dataset

Open GSE56581 in finder → Find more human methylation datasets →

Download · which file do I need?

Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

Series matrix ↓

2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need.

All supplementary files ↗

3 · The original raw files

Whole study · RAW.tar

Everything the authors deposited as one archive (GSE56581_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.

Whole study · RAW.tar ↓

What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.

Also filed as BioProject PRJNA243975. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 25404168) ↗

Samples in this study

The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.

+ 214 more — browse all 214 samples with per-sample file links →

Datasets on a similar topic

GSE56046 Transcriptomics and methylomics of human monocytes [methylome] 1202 samples shares methylomics, methylome
GSE56047 Transcriptomics and methylomics of human monocytes 2832 samples shares methylomics
GSE71244 Integrative analysis of methylome and transcriptome in human blood identifies extensive sex and immune cell-specific differentially methylated regions [methylation] 24 samples shares methylome
GSE56045 Transcriptomics and methylomics of human monocytes [transcriptome] 1202 samples shares methylomics
GSE241900 Quartet Methylomics 117 samples shares methylomics
GSE49277 Genome-scale methylome profiling of adrenocortical carcinomas (ACC) and adenomas (ACA) 81 samples shares methylome
GSE63818 The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells 364 samples shares methylome
GSE149250 Pancreatic Ductal Adenocarcinoma methylome analysis identifies differentially methylated genes in the Calcium signaling pathway and early methylation alterations. 15 samples shares methylome

Search all human methylation datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.