Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed
RNA-seq (gene expression) · human · 25 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 25 samples: 5 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE65926_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA275421 and SRA study SRP055027. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 5 replicated groups read from 25 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM1611263 P19_Day_0 P19_Day
- GSM1611264 P19_Day_2 P19_Day
- GSM1611265 P19_Day_4 P19_Day
- GSM1611266 P19_Day_12 P19_Day
- GSM1665895 P19 exp2 day 0 P19 exp2 day
- GSM1665896 P19 exp2 day 4 P19 exp2 day
- GSM1665897 P19 exp2 day 12 P19 exp2 day
- GSM1665898 fractionation, brain_lysate
- GSM1665899 fractionation, synaptoneurosomes
- GSM1665900 fractionation, cytoplasm
- GSM1665901 primary neurons, day 1 primary neurons, day
- GSM1665902 primary neurons, day 7 primary neurons, day
- GSM1665903 primary neurons, day 14 primary neurons, day
- GSM1665904 primary neurons, day 21 primary neurons, day
- GSM1665905 primary neurons, day 28 primary neurons, day
- GSM1665906 brain regions, hippocampus
- GSM1665907 brain regions, cerebellum
- GSM1665908 brain regions, prefrontal cortex
- GSM1665909 brain regions, olfactory bulb
- GSM1665910 SH-SY5Y exp1 day 0 SH-SY5Y exp1 day
- GSM1665911 SH-SY5Y exp1 day 2 SH-SY5Y exp1 day
- GSM1665912 SH-SY5Y exp1 day 4 SH-SY5Y exp1 day
- GSM1665913 SH-SY5Y exp2 day 0 SH-SY5Y exp2 day
- GSM1665914 SH-SY5Y exp2 day 4 SH-SY5Y exp2 day
- GSM1665915 SH-SY5Y exp2 day 8 SH-SY5Y exp2 day
- GSE47966 Global epigenomic reconfiguration during mammalian brain development 65 samples shares mammalian, brain
- GSE35156 Conserved Topological Domains in Mammalian Genomes Identified by High-resolution Analysis of Chromatin Interactions 9 samples shares mammalian, conserved
- GSE259220 Cas13bt3 knockdown of VEGFA mRNA in mammalian cells and mouse retina [RNA-Seq] 61 samples shares mammalian
- GSE238159 Conserved long noncoding RNA TILAM promotes liver fibrosis in humans and mice. 18 samples shares conserved
- GSE271926 Evaluation of the Mammalian Aquaporin Inhibitors Auphen and Z433927330 in Treating Breast Cancer 16 samples shares mammalian
- GSE97179 Single Cell Methylome Signatures Reveal Distinct Neuronal Populations and Regulatory Elements in the Mammalian Cortex 6172 samples shares mammalian
- GSE325170 A Universal 6iL/E4 Culture System for Deriving and Maintaining Embryonic Stem Cells Across Mammalian Species 2 samples shares mammalian
- GSE318290 Identification of conserved mecciRNAs 2 samples shares conserved
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.