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Expression data of induced sputum from Unbiased BIOmarkers in Prediction of REspiratory Disease outcomes (U-BIOPRED) Project

GSE76262 Homo sapiens (human) Expression microarray 139 samples Submitted 2016/12/31 Platform GPL13158
At a glance

Expression microarray · human · 139 samples

What it is
Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
Organism
Homo sapiens (human)
Samples
139 samples: 93 × induced sputum_severe vs 25 × induced sputum_moderate vs 21 × induced sputum_healthy controlGroups are read from the sample names, not from the paper. Check the list below.
Data you can get
A processed expression table (series matrix) and the array files, from NCBI.
Summary (written by the submitters)
Asthma is a heterogeneous disease requiring understandings at molecular level that characterizes subgroups of patients with specific biomarkers to faciliate the development of targeted thearpies. We used Affymetrix U133 Plus 2.0 PM only arrays to explore the gene expression profile from induced sputum cells of 118 moderate/severe asthmatic patients and 21 healthy controls.
This dataset
Open GSE76262 in finder → Find more human microarray datasets →
Download · which file do I need?

Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

Series matrix ↓
2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need.

All supplementary files ↗
3 · The original raw files

Whole study · RAW.tar

Everything the authors deposited as one archive (GSE76262_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.

Whole study · RAW.tar ↓

What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.

Also filed as BioProject PRJNA306744. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 28179442) ↗
Study design
93 × induced sputum_severe vs 25 × induced sputum_moderate vs 21 × induced sputum_healthy control

Supports a between-group comparison across 139 samples.

How we read this: 3 replicated groups read from 139 sample titles; they account for 139 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.

Samples in this study

+ 99 more — browse all 139 samples with per-sample file links →

Datasets on a similar topic

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