The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-M6A Seq
human · 20 samples
- Organism
- Homo sapiens (human)
- Samples
- 20 samples: 20 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI.
Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need.
Whole study · RAW.tar
Everything the authors deposited as one archive (GSE87190_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.
Also filed as BioProject PRJNA343813 and SRA study SRP090254. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 20 sample titles: 20 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM2324291 NOMO-1 PBS input
- GSM2324292 NOMO-1 PBS m6A-seq
- GSM2324293 NOMO-1 R-2HG input
- GSM2324294 NOMO-1 R-2HG m6A-seq
- GSM2324295 MA9.3ITD shNS-1-PBS input
- GSM2324296 MA9.3ITD shNS-1-PBS m6A-seq
- GSM2324297 MA9.3ITD shNS-1-R-2HG input
- GSM2324298 MA9.3ITD shNS-1-R-2HG m6A-seq
- GSM2324299 MA9.3ITD shFTO-1-PBS input
- GSM2324300 MA9.3ITD shFTO-1-PBS m6A-seq
- GSM2324301 MA9.3ITD shFTO-1-R-2HG input
- GSM2324302 MA9.3ITD shFTO-1-R-2HG m6A-seq
- GSM2324303 MA9.3RAS Ctrl-PBS input
- GSM2324304 MA9.3RAS Ctrl-PBS m6A-seq
- GSM2324305 MA9.3RAS Ctrl-R-2HG input
- GSM2324306 MA9.3RAS Ctrl-R-2HG m6A-seq
- GSM2324307 MA9.3RAS FTO-PBS input
- GSM2324308 MA9.3RAS FTO-PBS m6A-seq
- GSM2324309 MA9.3RAS FTO-R-2HG input
- GSM2324310 MA9.3RAS FTO-R-2HG m6A-seq
- GSE87187 The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-Resistant, sensitive and healthy control 13 samples shares r-2hg, anti-leukemic, depends, acting, mrna
- GSE87189 The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 12 samples shares r-2hg, anti-leukemic, depends, acting, mrna
- GSE324546 Anti-leukemic effect of MAR-3.6.2, a novel RAN inhibitor, on AML-LSCs by targeting RAN. 18 samples shares anti-leukemic
- GSE282364 Anti-leukemic effect of TGN-1062, a novel CDK7 inhibitor, on AML-leukemic stem cells by targeting RNA modification and Mitochondrial metabolism 12 samples shares anti-leukemic
- GSE296195 Anti-Leukemic Effects of Velcrin in SLFN12-Expressing Acute Myeloid Leukemia 8 samples shares anti-leukemic
- GSE319868 A novel potent and selective GCN2 inhibitor, APL-4098, has anti-leukemic activity through dysregulation of mitochondrial function 64 samples shares anti-leukemic
- GSE305063 FOXP3 Expression Depends on Cell-Type Specific Cis-Regulatory Element and Transcription Factor Circuitry [human_Tconv_ChIP-seq] 38 samples shares depends
- GSE330283 Endothelial transcriptome remodeling by young and senescent MSCs depends on co-culture mode, ECM, and secreted factors 27 samples shares depends
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.