Enhancer reprogramming promotes pancreatic cancer progression and metastasis [ChIP-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 90 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 90 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE99284_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA387949 and SRA study SRP107986. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 90 more — browse all 90 samples with per-sample file links →
- GSE245731 HNF4G and FOXA1 are context-specific drivers of pancreatic cancer progression [ChIP-seq] 172 samples shares progression, pancreatic, chip-seq
- GSE279644 BCR::ABL1-induced enhancer reprogramming uncovers hypersensitivity of Ph+B-ALL cells to enhancer-targeting drugs [ChIP-Seq] 91 samples shares reprogramming, enhancer, chip-seq
- GSE228805 Engrailed-1 Promotes Pancreatic Cancer Metastasis 48 samples shares pancreatic, metastasis, promotes
- GSE115462 TP63-mediated enhancer reprogramming drives the squamous subtype of pancreatic ductal adenocarcinoma (RNA-seq) 42 samples shares reprogramming, pancreatic, enhancer
- GSE234078 A super-enhancer regulated RNA-binding protein cascade drives pancreatic cancer 24 samples shares pancreatic, enhancer
- GSE245734 HNF4G and FOXA1 are context-specific drivers of pancreatic cancer progression 225 samples shares progression, pancreatic
- GSE157927 Triptolide Targets Super-Enhancer Networks in Pancreatic Cancer Cells and Cancer Associated Fibroblasts 81 samples shares pancreatic, enhancer
- GSE295336 H2BE113K mutation promotes breast cancer metastasis through modulating chromatin dynamics 77 samples shares metastasis, promotes
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.