GEO series
Mutual repression of the RNA-binding protein PCBP2 and long non-coding RNAs in induced pluripotent stem cells
GSE139626
Homo sapiens
Expression profiling by high throughput sequencing
10 samples
2025/12/31
GPL18573
Summary
Data from our lab and others have previously implicated that C-rich elements (CREs) are enriched in mRNAs that are destabilized in pluripotent stem cells compared to fibroblasts. PCBP2 is an RNA-binding protein that interacts with CREs and can influence mRNA degradation. We sought to decipher the influence of PCBP2 on gene expression in human induced pluripotent stem cells (iPSC).
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