GEO series

Expression data from Foxl2 wild-type and mutant ovaries and testes

GSE16853 Mus musculus Expression profiling by array 12 samples Submitted 2010/01/01 Platform GPL1261Platform GPL6246

Summary

Foxl2 is a forkhead transcription factor expressed only in the female, but not in the male gonad. We have created mice homozygous mutant for the Foxl2 gene (KO) as well as mice carrying a conditional mutant Foxl2 allele (floxed). The expression profiles of conventional Foxl2 knockout and wildtype ovaries were compared at P3, using the Affy Mouse Genome 430 2.0 Array. Adult wildtype and conditional mutant (Foxl2 floxed x RosaCre-EBD treated with tamoxifen) ovaries were compared to adult wildtype testes using the Affymetrix Mouse Gene 1.0 ST Array. Both experiments (KO/WT P3 and Mutant/WT/Testis Adult were also compared to each other.)

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Direct links to NCBI, no account and no request form: the whole study as GSE16853_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 12 samples.

Whole study · RAW.tar ↓ Series matrix ↓ All supplementary files ↗

Also filed as BioProject PRJNA117553. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 20005806) ↗

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