← BioTransfer GEO Dataset Finder
GEO series

Expression data from monocytes and monocytic myeloid-derived suppressor cells from HNSCC patients and healthy donors [RNA-seq]

GSE183854 Homo sapiens Expression profiling by high throughput sequencing 17 samples Submitted 2021/11/11 Platform GPL18573
Summary
A better understanding of the mechanisms that induce and drive human suppressive myeloid cells, such as myeloid-derived suppressor cells (MDSCs) and tolerogenic dendritic cells (TolDCs), stimulates therapeutic approaches that intent to restore the immune balance in patients. Here, we compared gene profiles of in vitro generated and isolated M-MDSCs derived from cancer patients to monocytes isolated from cancer patients and healthy donors.
Published in
Myeloid-derived suppressor cells and tolerogenic dendritic cells are distinctively induced by PI3K and Wnt signaling pathways
van Wigcheren GF, Cuenca-Escalona J, Stelloo S et al. · The Journal of biological chemistry 2023 · PMID 37739035 · doi:10.1016/j.jbc.2023.105276
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE183854_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 17 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA765711 and SRA study SRP338479. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 17 more — browse all 17 samples with per-sample file links →

Similar datasets

Search all human RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.