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Droplet-based RNA sequencing of single cells from injured and regenerating skeletal muscles of young and aged mice

GSE191188 Mus musculus Expression profiling by high throughput sequencing 5 samples Submitted 2025/06/16 Platform GPL24247Platform GPL19057
Summary
Single-cell RNA sequencing of cells from healthy and notexin injured muscles in a time course. To ensure we capture a wide variety of cell types and myogenic states, cells from uninjured and injured timepoints were mixed for each droplet-generation and sequencing run.
Published in
Multiomic profiling reveals that prostaglandin E2 reverses aged muscle stem cell dysfunction, leading to increased regeneration and strength
Wang YX, Palla AR, Ho ATV et al. · Cell stem cell 2025 · PMID 40513560 · doi:10.1016/j.stem.2025.05.012
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Also filed as BioProject PRJNA789986 and SRA study SRP351436. Searching any of these in the dataset finder brings you back here.

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