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Transforming Growth Factor-β (TGFβ) Prevents Hypertension-Induced Aortic Dissection in Adult Mice via Extracellular Matrix Production (Single cells KO vs. WT SMC)

GSE194083 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2025/02/27 Platform GPL24247
Summary
We report single-cell RNA-seq data of Myh11 lineage marked smooth muscle cells (SMCs) from murine aortas at 1 week after conditional disruption of TGFβ signaling versus controls
Published in
Heterogeneous Cardiac-Derived and Neural Crest-Derived Aortic Smooth Muscle Cells Exhibit Similar Transcriptional Changes After TGFβ Signaling Disruption
Ren P, Jiang B, Hassab AHM et al. · Arteriosclerosis, thrombosis, and vascular biology 2025 · PMID 39697172 · doi:10.1161/ATVBAHA.124.321706
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Also filed as BioProject PRJNA799019 and SRA study SRP355988. Searching any of these in the dataset finder brings you back here.

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