Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa (Illumina)
DNA methylation · human · 7 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Homo sapiens (human)
- Samples
- 7 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE19889_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA124021 and SRA study SRP002182. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 7 more — browse all 7 samples with per-sample file links →
- GSE277183 RNA Polymerase II coordinates histone deacetylation at active promoters 158 samples shares promoters, histone, active
- GSE29505 Custom Illumina array DNA methylation analysis of 384 CpGs across five cancer types 290 samples shares methylation, illumina
- GSE289805 Histone H4 lysine 20 tri-methylation safeguards breast cancer lineage fidelity and unfolded protein response [ChIP-seq/ATAC-seq] 126 samples shares methylation, histone
- GSE65820 Whole genome characterisation of chemoresistant ovarian cancer [Illumina_450K_Methylation] 121 samples shares methylation, illumina
- GSE67751 Blood Illumina Inf 450 DNA methylation samples from HIV+ and HIV- human subjects 92 samples shares methylation, illumina
- GSE274999 Clinical response to azacitidine in MDS is associated with distinct DNA methylation changes in HSPCs [RNA-Seq] 52 samples shares methylation, distinct
- GSE298243 Single-Cell Profiling of DNA Methylation in Autism Spectrum Disorder Prefrontal Cortex Reveals Distinct Regulatory and Aging Signatures 49 samples shares methylation, distinct
- GSE200514 A Conserved Switch to Less Catalytically Active Polycomb Repressive Complexes in non-dividing cells 46 samples shares repressive, active
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.