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Role of GLI-signaling in the postnatal cardiomyocyte development

GSE201589 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/11/27 Platform GPL24247
Summary
Developmentally, we found downregulation of GLI-signaling in adult human CM, adult murine CM, and in late-stage hiPSC-CM. To investigate the role of GLI-signaling in early-stage cardiomyocyte, we inhibited GLI-signaling and undertook bulkRNAseq analysis at two distinct levels of inhibitions.
Published in
The HH-GLI2-CKS1B network regulates the proliferation-to-maturation transition of cardiomyocytes
Waldron CJ, Kelly LA, Stan N et al. · Stem cells translational medicine 2024 · PMID 38761090 · doi:10.1093/stcltm/szae032
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Also filed as BioProject PRJNA832267 and SRA study SRP372335. Searching any of these in the dataset finder brings you back here.

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