GEO series
Mouse single positive thymocyte bulk RNA-seq from Kmt2d knockout and control littermates.
GSE205285
Mus musculus
Expression profiling by high throughput sequencing; Third-party reanalysis
18 samples
2024/05/03
GPL24247
Summary
To evaluate the hypothesis that dysregulated thymocyte development contributes to immune deficiencies in individuals with KS1. We generated bulk murine CD4+ or CD8+ single positive thymocyte RNA-seq data from cells which lack the histone methyltransferase, Kmt2d SET domain (exons 50/51), with a conditional Cre-recombinase driven by Lck-CreMar (T cell specific) or Vav1-iCre (hematopoietic). Expression profiling by high throughput sequencing.
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Paper (PMID 38765012) ↗
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