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Claudin2 Upregulation: IBD and colitis-associated colon cancer

GSE207221 Mus musculus (mouse) Expression microarray 36 samples Submitted 2025/06/27 Platform GPL24247
At a glance

Expression microarray · mouse · 36 samples

What it is
Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
Organism
Mus musculus (mouse)
Samples
36 samples: 9 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
Data you can get
A processed expression table (series matrix) and the array files, from NCBI.
SuperSeries — this record groups several sub-series.
Summary (written by the submitters)
This SuperSeries is composed of the SubSeries listed below.
This dataset
Download · which file do I need?

Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE207221_RAW.tar (it can run to tens of gigabytes).

3 · Start from the raw reads

Raw sequencing reads

The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.

What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.

Also filed as BioProject PRJNA854172 and SRA study SRP384233. Searching any of these in the dataset finder brings you back here.

Study design
9 conditions, mostly in duplicate
R1_ACAGTG_L ×2 R2_GCCAAT_L ×2 R3_CTTGTA_L ×2 R4_GTGAAA_L ×2 R5_CGATGT_L ×2 R6_TGACCA_L ×2 R7_CAGATC_L ×2 R8_CCGTCC_L ×2 +19 more

Supports a between-group comparison across 18 samples.

How we read this: 9 replicated groups read from 36 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.

Samples in this study
Datasets on a similar topic

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