Requirements for Establishment and Epigenetic Stability of Mammalian Heterochromatin [ChIP-Seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 18 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 5 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Requirements for establishment and epigenetic stability of mammalian heterochromatinMolecular cell · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE212153_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA874110 and SRA study SRP394290. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
How we read this: 5 replicated groups read from 18 sample titles; they account for 10 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6510276 mESC, H3K9me3, WT, rep1 mESC, H3K9me3, WT,
- GSM6510277 mESC, H3K9me3, WT, rep2 mESC, H3K9me3, WT,
- GSM6510278 mESC, H3K9me3, DHX9KO, rep1 mESC, H3K9me3, DHX9KO,
- GSM6510279 mESC, H3K9me3, DHX9KO, rep2 mESC, H3K9me3, DHX9KO,
- GSM6510280 mESC, INPUT (H3K9me3), WT
- GSM6510281 mESC, INPUT (H3K9me3), DHX9KO
- GSM6510282 mESC, H3K9me3, before establishment, WT
- GSM6510283 mESC, H3K9me3, established before maintenance, WT
- GSM6510284 mESC, H3K9me3, established before maintenance, DHX9KO
- GSM6510285 mESC, H3K9me3, established before maintenance, UHRF1KO
- GSM6510286 mESC, H3K9me3, maintenance, WT, rep1 mESC, H3K9me3, maintena…
- GSM6510287 mESC, H3K9me3, maintenance, WT, rep2 mESC, H3K9me3, maintena…
- GSM6510288 mESC, H3K9me3, maintenance, DHX9KO, rep1 mESC, H3K9me3, maintena…
- GSM6510289 mESC, H3K9me3, maintenance, DHX9KO, rep2 mESC, H3K9me3, maintena…
- GSM6510290 mESC, H3K9me3, maintenance, UHRF1KO
- GSM8187177 mESC, H3K9me3, UHRF1KO, rep1 mESC, H3K9me3, UHRF1KO,
- GSM8187178 mESC, H3K9me3, UHRF1KO, rep2 mESC, H3K9me3, UHRF1KO,
- GSM8187179 mESC, INPUT (H3K9me3), UHRF1KO
- GSE264193 H3K27 dimethylation dynamics reveal stepwise establishment of facultative heterochromatin in early mouse embryos [ChIP-seq] 57 samples shares heterochromatin, establishment, chip-seq
- GSE244496 Establishment of nuclear organization in mouse embryos is regulated by multiple and redundant epigenetic pathways. 183 samples shares establishment, epigenetic
- GSE289642 Noncanonical PRC2 chromatin association reveals a key role of EZHIP in intergenerational epigenetic memory transition [ChIP-Seq, Cut & Run] 107 samples shares epigenetic, chip-seq
- GSE303384 Mechanism of maintenance and establishment of repression by the Mtg16 tumor suppressor [CUT&RUN, ChIP-Seq] 92 samples shares establishment, chip-seq
- GSE329244 Polycomb erasers BAP1 and UTX are dispensable for rapid bivalent gene activation but essential for enhancer establishment [ChIP-seq] 64 samples shares establishment, chip-seq
- GSE289108 Neurons undergo IFNγ-driven persistent epigenetic shifts and synaptic remodeling in the inflamed brain [ChIP-Seq] 57 samples shares epigenetic, chip-seq
- GSE304113 Establishment of sex-specific liver transcriptomes and H3K9me3 profiles during sexual maturity: the impact of maternal obesity [ChIP-seq] 36 samples shares establishment, chip-seq
- GSE275917 Nup153 regulates neuronal responsiveness through HDAC1-mediated epigenetic modulation [ChIP-seq] 17 samples shares epigenetic, chip-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.