84-B10 alleviates cisplatin-induced acute kidney injury in mice
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 4 × Vehicle vs 4 × Cisplatin vs 4 × Cisplatin + 84-B10Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE213473_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA880900 and SRA study SRP397501. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 3 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6586867 Vehicle biological replicate 1 Vehicle
- GSM6586868 Vehicle biological replicate 2 Vehicle
- GSM6586869 Vehicle biological replicate 3 Vehicle
- GSM6586870 Vehicle biological replicate 4 Vehicle
- GSM6586871 Cisplatin biological replicate 1 Cisplatin
- GSM6586872 Cisplatin biological replicate 2 Cisplatin
- GSM6586873 Cisplatin biological replicate 3 Cisplatin
- GSM6586874 Cisplatin biological replicate 4 Cisplatin
- GSM6586875 Cisplatin + 84-B10 biological replicate 1 Cisplatin + 84-B10
- GSM6586876 Cisplatin + 84-B10 biological replicate 2 Cisplatin + 84-B10
- GSM6586877 Cisplatin + 84-B10 biological replicate 3 Cisplatin + 84-B10
- GSM6586878 Cisplatin + 84-B10 biological replicate 4 Cisplatin + 84-B10
- GSE341145 7-hydroxycoumarin-β-D-glucuronide protects against cisplatin-induced acute kidney injury via inhibiting p38 MAPK-mediated apoptosis in mice 20 samples shares cisplatin-induced, kidney, injury, acute
- GSE341526 Atractylenolide III Alleviates Cisplatin-Induced Acute Liver Injury by Regulating Gut-Liver Axis Through Inhibiting ACT1/TRAF6/NF-κB-Mediated IL-17 Pathway 9 samples shares cisplatin-induced, alleviates, injury, acute
- GSE289432 Y665F variant of mouse STAT5b protects against acute kidney injury through transcriptomic shifts in renal gene expression 32 samples shares kidney, injury, acute
- GSE239287 Single-cell transcriptome sequencing of macrophages in acute kidney injury(AKI) to chronic kidney dieases(CKD) 17 samples shares kidney, injury, acute
- GSE202753 DsbA-L deficiency attenuates LPS-induced acute kidney injury via NF-κB/AP-1 regulation of macrophage polarization 13 samples shares kidney, injury, acute
- GSE309904 Acute kidney injury following fatty liver ischemia-reperfusion injury: indirect protection by hepatic ferroptosis inhibition 12 samples shares kidney, injury, acute
- GSE243633 Runt-related Transcription Factor 1 (RUNX1) is a mediator of acute kidney injury 12 samples shares kidney, injury, acute
- GSE333173 Ketogenic Diet Alleviates Acute Radiation-Induced Intestinal Injury through JAK2/STAT3/RORγt/IL-17A Signaling Pathway via Gut Microbiome 9 samples shares alleviates, injury, acute
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.