Runt-related Transcription Factor 1 (RUNX1) is a mediator of acute kidney injury
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × Control vs 3 × Runx1 vs 3 × LPS vs 2 × LPS RUNX1Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Runt-related transcription factor 1 (RUNX1) is a mediator of acute kidney injuryThe Journal of pathology · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE243633_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1019297 and SRA study SRP462241. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 11 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 11 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7792062 Control 0 Control
- GSM7792063 Control 1 Control
- GSM7792064 Control 2 Control
- GSM7792065 Runx1 0 Runx1
- GSM7792066 Runx1 1 Runx1
- GSM7792067 Runx1 2 Runx1
- GSM7792068 LPS RUNX1 0 LPS RUNX1
- GSM7792069 LPS RUNX1 1 LPS RUNX1
- GSM7792070 LPS RUNX3 2
- GSM7792071 LPS 0 LPS
- GSM7792072 LPS 1 LPS
- GSM7792073 LPS 2 LPS
- GSE286046 Asymmetric Histone Inheritance Regulates Differential Transcription Re-initiation and Cell Fate Decisions in Mouse Olfactory Horizontal Basal Cells 96 samples shares transcription, factor
- GSE300113 Heterogenous microglial reactivity contrasts with stable vascular transcriptional programs in mouse models of Alzheimer’s, CADASIL, and Traumatic Brain Injury (Main dataset) 59 samples shares transcription, injury
- GSE281037 Large-scale transcriptomic analyses reveal downstream target genes of ZFY1 and ZFY2 transcription factors in male germ cells 48 samples shares transcription, factor
- GSE220665 The Transcriptional Cofactor SKI Regulates Medullary Thymic Epithelial Cell Differentiation and Peripheral T Cell Responses 42 samples shares transcription, factor
- GSE327967 Transcriptional regulation of the main olfactory epithelium by environmental olfactory exposures 34 samples shares transcription, factor
- GSE270036 Investigate the functions of core pluripotency transcription factors in embryonic stem cells 30 samples shares transcription, factor
- GSE245838 Anchored screening identifies transcription factor blueprints underlying dendritic cell diversity and subset-specific anti-tumor immunity [mouse scRNA-seq] 21 samples shares transcription, factor
- GSE322779 Transcription factor TFEB antagonizes cardiac hypertrophy and failure by enhancing lysosomal capacity and mitochondrial function 16 samples shares transcription, factor
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.